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Wednesday, July 29, 2020 | History

3 edition of The IUPHAR compendium of receptor characterization and classification found in the catalog.

The IUPHAR compendium of receptor characterization and classification

The IUPHAR compendium of receptor characterization and classification

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Published by IUPHAR Media in London .
Written in English


Edition Notes

Statement[compiled by the IUPHAR Committee on Receptor Nomenclature and Drug Classification].
ContributionsInternational Union of Pharmacology. Committee on Receptor Nomenclature and Drug Classification.
The Physical Object
Pagination396p. ;
Number of Pages396
ID Numbers
Open LibraryOL18537776M
ISBN 100953351033
OCLC/WorldCa50429018

  Humphrey PPA, Khakh BS, Kennedy C, King BF, Burnstock G () The IUPHAR Compendium of Receptor Characterization and Classification. Pub. Pub. Cited by: The IUPHAR Compendium of Receptor Characterization and Classification (2nd ed.). London: IUPHAR Media. pp. – Jump up ^ "Opioid receptors". IUPHAR Database. International Union of Pharmacology (). Jump up ^ Dietis N, Rowbotham D, Lambert D (May ). "Opioid receptor subtypes: fact or artifact?". British Journal of Anaesthesia.

Buspirone, sold under the brand name Buspar among others, is a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder. Benefits support its short term use. It has not been found to be effective in treating psychosis. It is taken by mouth, and it Metabolism: Liver (via CYP3A4). In: Girdlestone D (ed) The IUPHAR compendium of receptor characterization and classification. IUPHAR Media, London, pp 80–86 Google Scholar De Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T () International union of pharmacology.

Background and objectives: toxic liver injury results in nitrooxidative stress. Melatonin is a potent free radical scavenger, an inducible nitric oxide synthase (iNOS) inhibitor and an activator of antioxidant enzymes. The aim of this study was to investigate the hepatoprotective effect of exogenous melatonin on animals with acute toxic : Oleksandra Oleshchuk, Yana Ivankiv, Halina Falfushynska, Alla Mudra, Nataliya Lisnychuk. Martin GR () 5-Hydroxytryptamine receptors. NC-IUPHAR subcommittee for 5-hydroxytryptamine (serotonin) receptors. In Gridlestone D (ed) The IUPHAR Compendium of Receptor Characterization and Classification. IUPHAR Media, London, pp – Google Scholar.


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The IUPHAR compendium of receptor characterization and classification Download PDF EPUB FB2

ISBN: OCLC Number: Description: vii, pages ; 30 cm: Other Titles: International Union of Pharmacology compendium of receptor characterization and.

The IUPHAR compendium of receptor characterization and classification by,IUPHAR Media edition, in English - 2nd : NC-IUPHAR (the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification) issues guidelines for the nomenclature and classification of (human) biological targets, including the targets of current and future prescription medicines.

NC-IUPHAR also works to facilitate the interface between the discovery of new sequences from the Human. The IUPHAR Compendium of the Pharmacology and Classification of the Nuclear Receptor Superfamily This volume, edited for IUPHAR by Vincent Laudet, is.

A primary purpose of IUPHAR is providing global free access to a major, on-line repository of characterization data for receptors, ion channels, enzyme target classes and drugs through the Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), established in Type: INGO.

The IUPHAR/BPS Guide to Pharmacology. GPCR families. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of drug targets.

Anti-N-Methyl-D-Aspartate Receptor Encephalitis with Concomitant Detection of Epstein-Barr Virus. Neuza Soares, Emanuel Dias, Mariana Formigo, P.

Torres-Ramalho, Luis Braz, Reina-Couto Marta. DOI: /nm Downloads Views. Pub. The IUPHAR/BPS Guide to PHARMACOLOGY is an open-access website, acting as a portal to information on the biological targets of licensed drugs and other small molecules.

The Guide to PHARMACOLOGY (with GtoPdb being the standard abbreviation) is developed as a joint venture between the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Data types captured: Target nomenclature, pharmacological data, ligand structures.

On the basis of molecular biological characterization, five subtypes (M 1 –M 5) of mAChR genes have been identified (Bonner et al., ; Liao et al., ), with each of these receptor proteins encoded by an intronless gene exhibiting a unique pharmacological profile (Bonner et al., ; Peralta et al., a).

The mAChRs can be divided Cited by: Abstract. Quantification of radioligand binding by exposing labeled tissue sections to phosphor screens in cassettes is similar to autoradiography using radiation sensitive film (see Chapters 5 and 7).The major advantage of phosphor screens over film is the greatly increased sensitivity with exposure times reduced by at least one order of magnitude (2, 3).Cited by: 5.

London: IUPHAR Media Ltd.; In: The IUPHAR Compendium of Receptor Characterization and Classification; pp. – Holzer P. Opioid receptors in the gastrointestinal tract. Regul Pept. ; ()– [PMC free article]Cited by: Yu FH, Yarov-Yarovoy V, Gutman GA et al () Overview of molecular relationships in 2 How to Use the IUPHAR Receptor Database to Navigate Pharmacological Data the voltage-gated ion channel.

Witt-Enderby, P.A. and Dubocovich, M.L. Characterization and regulation of the human ML 1A melatonin receptor stably expressed in Chinese hamster ovary cells. Mol Pharrnacol –, Mol Pharrnacol –, Cited by: The IUPHAR compendium of receptor characterization and classification ML Dubocovich, DP Cardinali, P Delagrange, DN Krause, AD Strosberg, IUPHAR Media, London, This registry is based on Gene Ontology Consortium's _abbs file (Revision ), NCBI db_xref format specification (Septem ) and many other sources, such as NCBI's Dbtag_db.

Many records originated from _abbs file are incomplete and need additional curation; not all of them are suitable for automatic processing by LSRN. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.

IUPHAR Compendium of Receptor Characterization and Classification, 2nd Edition (IUPHAR), Japanese Translation of IUPAC White Book on Chlorine (Special Issue of Pure and Applied Chemistry, Vol. 68, No. 9, ), The IUPHAR Compendium of Receptor Characterization and Classification.

London: International Union of Pharmacology Media, The IUPHAR Compendium of Receptor Characterization and Classification, International Union of Pharmacology Media, London () EF Ellis (Eds.), Allergy Principles and Practice (4th ed.), Mosby-Year Book Inc Cited by: This classification is based on the IUPHAR Compendium of Receptor Characterization and Classification.

Complete details are available in Alexander et al. Differences between the human and rat forms of the receptors are indicated by (h) and (r), by: The database provides a channel for the IUPHAR Nomenclature Committee (NC-IUPHAR) to provide recommendations on the nomenclature of receptors and ion channels, to document their properties and the ligands that are useful for receptor characterization.

Here we describe IUPHAR-DB’s main features and provide examples of techniques for navigating. ABSTRACT. Somatostatin is abundant in the mucosa and in the enteric nervous system of the gastrointestinal tract and in the pancreas.

In these tissues, it exerts a broad range of mainly inhibitory physiological actions in multiple targets, including endocrine glands, exocrine glands, smooth muscles, blood vessels, and immune cells, mediated by up to six somatostatin receptor subtypes.A zebrafish M 2 muscarinic acetylcholine receptor (mAChR) gene was cloned.

It encodes amino acids in a single exon. The derived amino acid sequence is % identical to its human homologue. Competitive binding studies of the zebrafish M 2 receptor and [3 H]‐NMS gave negative log dissociation constants (pK i) for each antagonist as follows: atropine ()>himbacine ()4‐DAMP ( Cited by: The pineal hormone, melatonin (N-acetylmethoxytryptamine), shows potent receptor-dependent and -independent actions, which participate in blood pressure regulation.

The antihypertensive effect of melatonin was demonstrated in experimental and clinical hypertension. Receptor-dependent effects are mediated predominantly through MT1 and MT2 G-protein coupled by: